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MANUKA DROPSLIMITED · NEW ZEALAND
Human randomized trialResearch archive · noindex2023 · Materials

Human research & reviews

Therapeutic Manuka Honey as an Adjunct to Non-Surgical Periodontal Therapy: A 12-Month Follow-Up, Split-Mouth Pilot Study

Authors: Opšivač D et al.

ARCHIVE NOTICE

A full-text editorial assessment has not yet been completed. This record preserves bibliographic and tested-material context only; consult the primary source for methods and results. No product, health or treatment claim is made.

Result handling

Consult the cited publication for the reported result. This archive does not interpret it as a product, health or treatment claim.

Study design

split-mouth randomized controlled pilot study

Oral and dental research

Tested material

Study-specific medical-grade honey, dressing, eye-care or oral preparation described by the publication; not The 3 Beez retail food product.

Limitations

Only 12 patients were analyzed, baseline plaque and bleeding differed, split-mouth carryover was possible, and the product combined therapeutic manuka honey with hydrogen peroxide.

Funding & conflicts

Not yet transcribed from the primary publication.

Applicability guardrail

Because Pocket Protect contains both manuka honey and hydrogen peroxide, this pilot cannot attribute the small clinical effect to honey alone.

Scientific reference

Opšivač D et al. (2023). Therapeutic Manuka Honey as an Adjunct to Non-Surgical Periodontal Therapy: A 12-Month Follow-Up, Split-Mouth Pilot Study. Materials. https://doi.org/10.3390/ma16031248

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Editorial record

Responsible publisher: Manuka Drops Limited. Record updated: 2026-08-28. Retraction check recorded: 2026-08-16. Retraction status: checked-no-retraction-signal. Editorial status: verified. Read the methodology.