Human research & reviews
The efficacy of honey or olive oil on the severity of oral mucositis and pain compared to placebo (standard care) in children with leukemia receiving intensive chemotherapy: A randomized controlled trial (RCT)
Authors: Badr LK et al.
ARCHIVE NOTICE
A full-text editorial assessment has not yet been completed. This record preserves bibliographic and tested-material context only; consult the primary source for methods and results. No product, health or treatment claim is made.
Result handling
Consult the cited publication for the reported result. This archive does not interpret it as a product, health or treatment claim.
Study design
Single-blind, three-arm randomized controlled trial (phase II)
Oral and dental research
Tested material
Manuka honey and olive oil in separate study groups for chemotherapy-associated oral mucositis in children with leukemia, compared with standard oral care. Product grade and sterilization are not established by the accessible abstract and publisher extracts; not a test of The 3 Beez retail food honey.
Limitations
Small, single-blind trial conducted at two university hospitals. The abstract describes 42 children; full participant flow, product specifications and a complete risk-of-bias assessment require the full report.
Funding & conflicts
Not yet transcribed from the primary publication.
Applicability guardrail
This small study addressed treatment of existing mucositis in children with leukemia, not general cancer prophylaxis, and the manuka product's medical-grade status was not clearly established.
Scientific reference
Badr LK et al. (2023). The efficacy of honey or olive oil on the severity of oral mucositis and pain compared to placebo (standard care) in children with leukemia receiving intensive chemotherapy: A randomized controlled trial (RCT). Journal of Pediatric Nursing. https://doi.org/10.1016/j.pedn.2022.12.003
Editorial record
Responsible publisher: Manuka Drops Limited. Record updated: 2026-09-16. Retraction check recorded: 2026-08-16. Retraction status: checked-no-retraction-signal. Editorial status: verified. Read the methodology.
Limited methods check: Publication abstract and publisher methods extracts, 2026-09-16. This checks study design and tested material only; it is not a complete editorial or retraction review.